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Demerol functions by binding to opioid receptors in the brain and spinal cord, thereby altering the perception of pain. These receptors are part of the central nervous system's pain control system, and their activation results in pain relief, sedation, and a sense of well-being. Unlike other opioids, Demerol has a unique metabolic pathway, as it is metabolized in the liver to produce a metabolite known as normeperidine, which can contribute to toxicity and side effects.